Full-time

Senior Python Backend Developer

1/18/2026

The Senior Python backend developer will design and implement core services, optimize data workflows, and contribute to architecture decisions for mission-critical applications. They will also mentor other developers and collaborate with cross-functional teams to deliver solutions.

Working Hours

40 hours/week

Company Size

51-200 employees

Language

English

Visa Sponsorship

About The Company

CytoReason is a tech company transforming biopharma’s decision-making from trial and error to data-driven using an AI Platform of computational disease models. With its extensive database of public and proprietary data, the company maps human diseases – tissue by tissue and cell by cell. Researchers of all levels rely on CytoReason’s technology to make data-driven decisions across the drug development life cycle. Scientists can identify potential targets, prioritize indications, and stratify patient populations. Program leaders can compare drugs across multiple diseases or multiple drugs within a single disease. C-level executives can gain valuable tools to manage and optimize entire drug portfolios.

About the Role

We are seeking an experienced Senior Python Engineer to join our engineering team and drive the development of robust, scalable, and high-performance backend solutions. In this role, you will design and implement core services, optimize data workflows, and contribute to architecture decisions that support mission-critical applications. The ideal candidate brings deep expertise in Python, hands-on experience with distributed systems or data-intensive environments, and a passion for building reliable, production-grade software.

Responsibilities

Enabling the adoption of next-generation orchestration tool – Nextflow
Build software components to automate and reduce human work to annotate and design a model
Design and implement backend APIs using Nest.js, FastAPI integrating with data layers and external systems.
Contribute to and review frontend features in React, ensuring seamless integration with backend services.
Help design and shape the product, working closely with product managers, bioinformaticians, and other stakeholders to align technical decisions with product goals.
Mentor and support other developers through code reviews, internal discussions, clean code and technical guidance.
Collaborate cross-functionally with product, data, and infrastructure teams to define requirements and deliver solutions.
Write and maintain technical documentation and high-level designs

The Tech You’ll Work With:

Frontend: React, TypeScript, Tailwind CSS
Data & Storage: LakeFS, PostgreSQL, BigQuery
Cloud: Google Cloud Platform (GCP), AWS
Additional tools: Python, R (familiarity a plus, not required)
CI/CD & DevOps: Docker, Kubernetes

Requirements

7+ years of experience as a full-stack or backend-focused developer with experience in data-related product
Proficiency in Python / Node.js / Nest.js and experience with scalable API design.
Strong understanding of distributed systems, performance optimization, and cloud architectures.
Hands-on experience with modern frontend frameworks like React.
Strong communication and planning skills, with the ability to provide technical input during project scoping.
Track record of delivering efficiently in agile teams with shifting priorities.
Proactive mindset — someone who can take ownership, identify problems, and propose solutions.

Advantages

Experience with Python or R for data-related workflows.
Background in data-intensive systems or bioinformatics.
Hands-on experience with modern frontend frameworks, preferably React.
Familiarity with multi-cloud environments (GCP + AWS)

Key Skills

PythonNest.jsFastAPIReactData WorkflowsDistributed SystemsCloud ArchitecturesAPI DesignDockerKubernetesPostgreSQLBigQueryGoogle Cloud PlatformAWSTechnical DocumentationMentoring